Biofilm control and prophylaxis for dental units

Biofilms in dental units

  • The majority of microorganisms in water water-carrying systems live on the inner walls of pipes.
  • These microorganisms form so so-called biofilms in which they protect themselves from physical and chemical hazards.
  • Many antimicrobial substances and systems have been developed to eliminate or control microbial growth.
  • These are usually expensive to produce, ecologically problematic and selective in terms of their effectiveness and sometimes even ineffective in biofilm.
  • There is an increasing need for natural, ecologically and economically advantageous active ingredients.

Hydrogen peroxide

Advantages and disadvantages

Advantages

  • Residue-free decomposition
  • Ecological
  • Broad spectrum of activity
  • No resistance formation
  • Physiologically harmless (concentration dependent)

Disadvantages

  • High dosages required (spores, catalase activity, biofilm)
  • Unstable
  • No long long-term effect
  • Material incompatibilities at high dosage

WFX and active ingredient enhancement

What is WFX?

  • Viscous extract from surfactants and plant juice concentrates, produced using thermal processes
  • Microscopic hydrogel particles serve as packaging and transport vehicles
  • Micelles enable the active ingredient to penetrate the biofilm and break it down
  • The process is protected by patent law

How does the active ingredient get into the WFX packaging?

  • When WFX is added to the H2O2 solution, the active ingredient is enclosed in the WFX structures.
  • HYDRO L.O.G.® is a ready-to-use solution that already contains WFX.

What does enhancement mean?

  • Reduced consumption of active ingredients
  • Depot effect over time
  • Penetration into the biofilm
  • Electrical surface charge that promotes attraction between packaging and biofilms

Ingredients

The solution contains:

  • 1,7% Hydrogen peroxide
  • 0,2% Lactic acid
  • 0,05% WFX
  • Water

Biofilm control

  • The internationally patented HYDRO L.O.G.® formulation enables penetration into biofilms by attaching the active ingredient packaging to the biofilm via adhesion forces (charge)

  • In the biofilm, the micelle acts like a Trojan horse -the active ingredient can act directly on bacteria within the protective EPS matrix

Efficacy

Scientific publication in “Biofouling”

  • Antimicrobial effect of the new solution vs. H2O2 in biofilm
  • Comparison of the effectiveness of the solution and comparable commercial products in biofilm

BIOFOULING
»A novel micellar formulation based on natural plant extracts enhances the
efficacy of hydrogen peroxide against biofilms of Staphylococcus spp.
and Pseudomonas aeruginosa«
download the publication

Comparative trials at the Medical University of Vienna, University Clinic for Hospital Hygiene and Infection Control

Comparison new solution vs. H2O2

Comparison with other commercial products

Efficacy

  • The new solution eliminated all viable S. epidermidis, S. aureus and P. aeruginosa from mature, 24-hour-old biofilms after 5 minutes of exposure at the latest -> minus 8 log10 levels
  • The use of WFX increases the antimicrobial effectiveness of active ingredients such as H2O2
  • Comparable substances, such as Dentosept, have only shown an inferior and in some cases even selective antibacterial effect (at the same H2O2 concentrations)
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